bioinf tips!

Bioinformatics Tips from MB0503.

Section A - MCQs (Week 1 to Molecular Modelling) 20 Marks
Section B - Short Answer Questions 80 Marks

• 1 Question from Adrian
• 2 Questions from L.T
• 3 Questions from William

L.T Topics

1. Protein Analysis - Multiple Sequence Alignment

• identify similar areas
• how to use?
• weaknesses?
• information that can be derived

2. Genome Analysis - comparative analysis / genome of simple organism

3. Nucleotide Analysis - gene finding alogrithm (GenScan / MZEF)

• BLAST - similarity & identity
• the different tools under BLAST
• ORF - conceptual translation

Willam How's Topics

• Primary and secondary database
• Definitions and examples
• Elaborate on the different databases
• GenBank - nucleotide / annotation / variable DNA sequence (Partial genes, complete genes, complete genome)
• How is secondary information derived from primary?
• Explain the different forms of classification.

Jia You!
Carine(: